Research Articles
Breaking Cancer's Shield: How Targeting a Metabolic Enzyme Could Revolutionize Breast Cancer Treatment
Discover how blocking G6PD enzyme enhances breast cancer treatment effectiveness by disrupting cellular recycling mechanisms and overcoming drug resistance.
The Ancient Brew vs. The Modern Liver: Can a Plant Compound Turn the Tide?
Exploring how Salvianolic Acid A from traditional Chinese medicine may protect against alcoholic liver disease by promoting cellular cleanup processes.
The Kidney's Rescue Squad: How a Genetic Maestro Revives Cellular Cleanup After Injury
Discover how the SP1 protein and autophagy work together to protect kidneys from ischemia-reperfusion injury through the miR-205/PTEN/Akt pathway.
Sestrin2: The Cellular Shield That Makes Osteosarcoma Resistant to Chemotherapy
Exploring how Sestrin2-mediated autophagy contributes to drug resistance in osteosarcoma through endoplasmic reticulum stress mechanisms.
A Natural Molecule's Sneak Attack: How a Licorice Extract Fights Skin Cancer
Discover how Licochalcone A from licorice root activates autophagy to fight melanoma through the miR-142-3p/Rheb/mTOR pathway.
A Classic Drug's New Target: How an Old Malaria Pill Fights Lung Cancer
Discover how chloroquine, a traditional malaria drug, inhibits lung cancer growth by blocking autophagy and triggering apoptosis in cancer cells.
Beyond Death: How a Cell Death Protein Switches to Survival During Starvation
Discover how MLKL protein switches from cell death executioner to survival facilitator during starvation through autophagy activation with CaMKII.
How a Natural Blood Protein Could Revolutionize Atherosclerosis Treatment
Discover how recombinant thrombomodulin's anti-autophagic effects could transform atherosclerosis treatment by protecting endothelial cells.
Alpha Particles and Cellular Self-Destruction: A New Frontier in Multiple Myeloma Treatment
Discover how alpha particles trigger autophagy in multiple myeloma cells, offering new hope for targeted cancer therapy and precision medicine approaches.